Kayla Landers

Complex molecule total synthesis is integral to accessing new chemical space and unlocking the therapeutic potential of natural products that are otherwise inaccessible on large scales. Via total synthesis, the pressing need for new therapeutic targets can be addressed through modular syntheses that allow for derivatization and analogue synthesis. The Sarlah lab leverages total synthesis and methodology development to access molecules of biological value. My project focuses on the development of a borylative heck methodology that allows access to a privileged motif in terpenoid natural product synthesis, which can be elaborated to a plethora of molecules of biological relevance.